SignalsEverywhere: Windows 10 usb_open_error -12 Fix
The process to install an RTL-SDR dongle on Windows involves the simple step of running Zadig and installing the generic WinUSB drivers to the RTL-SDR, which shows up as "Bulk-In, Interface (Interface 0)" in Zadig.
However we find that people sometimes accidentally use Zadig to install WinUSB to "Bulk-In, Interface (Interface 1)" by mistake. Installing WinUSB to this interface can break your installation, and it can cause the RTL-SDR to display a "usb_open error -12" on command line software, and can cause problems connecting to the device on GUI software like SDR#.
Over on YouTube Corrosive from the SignalsEverywhere YouTube channel uploaded a very useful video that shows how to fix this problem.
RTL SDR Drivers On Windows 10 2019
As Gomer Pyle would say, Thank you! Thank you! Thank you!